Complete Adaptogenic Protocol
All four mushrooms. One complete protocol. Mind, energy, calm, and immune defence working together, every day.
Hericium erinaceus
Triggers NGF synthesis inside the brain. Builds focus, clarity, and creative thinking with daily compounding.
Cordyceps militaris
Expands ATP and VO₂ max for peak performance. Clean, sustained energy with zero stimulants and no crash.
Ganoderma lucidum
400+ triterpenes quiet cortisol and prepare the nervous system for deep, restorative overnight repair.
Lentinula edodes
Lentinan and eritadenine work in tandem for immune and gut lining resilience, every single day.
Fungi form a vast underground network called the Wood Wide Web, connecting trees across entire forests. Through this mycelium network, trees share nutrients, water and even chemical warning signals. A living internet beneath your feet.
Fungi predate dinosaurs by roughly 650 million years. The oldest known land fungi fossils date back 810 million years, making mushrooms one of the most ancient life forms still thriving on Earth today.
Lion's Mane stimulates the production of Nerve Growth Factor (NGF), a protein essential for the growth, maintenance and survival of neurons. It's one of the only known natural compounds capable of crossing the blood-brain barrier to trigger this regeneration.
Two unique compounds found exclusively in Lion's Mane - hericenones and erinacines - directly stimulate neuron repair. Studies have linked regular consumption to improved short-term memory, mental clarity and sharper concentration.
Lion's Mane has been shown to reduce symptoms of anxiety and mild depression by promoting healthy neurotransmitter production. In clinical trials, subjects reported significantly lower feelings of irritability and anxiety after just four weeks.
Tibetan herders first observed their yaks grazing on Cordyceps in the high Himalayan plateau, and noticed the animals became unusually energetic and strong. This led to the mushroom entering royal courts across Asia for over 2,000 years.
Cordyceps has been shown in peer-reviewed studies to increase VO2 max (the body's maximum oxygen uptake) by up to 7%. That's why elite endurance athletes and cyclists have used it to gain a legal competitive edge since the 1990s.
Wild Cordyceps is a parasitic fungus that infects insects, controls their nervous systems, and sprouts out of their bodies. It inspired the plot of the game and TV series 'The Last of Us.' The farmed variety used in supplements is entirely safe and non-parasitic.
In ancient China, Reishi was so rare and revered that it was reserved exclusively for emperors. It was called Lingzhi, meaning spiritual potency, and depicted in royal art as the symbol of good health, divine power, and everlasting life.
Reishi contains over 400 distinct bioactive triterpenes, compounds that modulate the immune system and reduce chronic inflammation at the molecular level. This is why it's studied extensively in relation to autoimmune conditions and long-term chronic stress.
Reishi spore powder, harvested from the mushroom's reproductive spores, is believed to be up to 75x more potent than the fruiting body itself. It takes a kilogram of Reishi to produce just one gram of spore powder, making it extraordinarily rare and valuable.
Shiitake contains exceptionally high levels of glutamate, the compound responsible for umami, the fifth taste. Japanese scientist Kikunae Ikeda first isolated and identified umami in 1908 using kombu, but shiitake was the original ingredient he set out to study.
Lentinan, a polysaccharide derived from Shiitake, is an approved medical treatment used in clinical oncology in Japan and China. It doesn't kill cancer cells directly. Instead it enhances the immune system's ability to identify and destroy abnormal cells.
Place a fresh Shiitake mushroom cap-side down in sunlight for just 15 minutes and its Vitamin D2 content skyrockets by up to 4,600 IU, from near zero to exceeding the daily recommended intake. No other plant-based food does this.
Every ingredient is certified non-GMO. No exceptions.
Built for potency. The dose in the capsule matches what the lab tested.
100% plant-based. Every ingredient, every capsule.
Ingredients chosen for what the research says, not what looks good on a label.
Independent labs test every batch before it ships.
Screened for heavy metals. Every batch, every time.
Shiitake has more peer-reviewed studies behind it than nearly any other medicinal mushroom. Lentinan, eritadenine and beta-glucans each target something specific: immune defence, cholesterol, your gut microbiome. Grown in Colombia. Zero synthetic inputs. No chemical processing.
Made in Colombia · Purest Non-Toxic Form
Tibetan herders noticed it first. Then royal courts. Then elite cyclists. Cordyceps raises ATP production and VO₂ max at the cellular level. Endurance athletes have used it legally for decades. No caffeine. No stimulants. Fruiting body only, grown at altitude in Colombia.
Made in Colombia · Purest Non-Toxic Form
Lion's Mane for focus. Cordyceps for energy. Reishi for recovery. Shiitake for immunity. Four clinically studied mushrooms, each doing something distinct, working together every day. Fruiting body only. Dual extracted. The full stack at a better price.
Made in Colombia · Purest Non-Toxic Form
I am so impressed with setasouls!! been using the reishi for a week and sleeping soo much better tbh 🍄✨
hey, just wanted to say these mushrooms are amazing. entirely changed my mornings 🤩
My focus is way better lately. No more mid day coffee crashes
thank you for making a clean product! been searching for something w/o filler for ages
ok but seriously how is the energy so consistent?? absolutely love it
started cordyceps 2 weeks ago and the difference at the gym is insane. more endurance, less fatigue. i don't know what you put in these but please never change the formula lol 💪
lions mane has been a game changer for work. i used to hit a wall at 3pm every day, now i just... keep going?? feels weird honestly haha
my partner actually noticed i seem calmer since i started reishi. that says a lot 😅
I am so impressed with setasouls!! been using the reishi for a week and sleeping soo much better tbh 🍄✨
hey, just wanted to say these mushrooms are amazing. entirely changed my mornings 🤩
My focus is way better lately. No more mid day coffee crashes
thank you for making a clean product! been searching for something w/o filler for ages
ok but seriously how is the energy so consistent?? absolutely love it
started cordyceps 2 weeks ago and the difference at the gym is insane. more endurance, less fatigue. i don't know what you put in these but please never change the formula lol 💪
lions mane has been a game changer for work. i used to hit a wall at 3pm every day, now i just... keep going?? feels weird honestly haha
my partner actually noticed i seem calmer since i started reishi. that says a lot 😅
Every mushroom supplement on the market was using mycelium grain: filler-heavy, low-potency, misleadingly labelled. We started Seta Souls because we wanted the real thing: fruiting-body only, dual-extracted in Colombia, verified before it ever ships.
Our process hasn't changed: hot water and alcohol extraction to preserve every bioactive compound, third-party testing for potency and heavy metals, and zero synthetic inputs from seed to capsule. This is what we'd take ourselves.
Nerve Growth Factor isn't a marketing claim: it's a protein that determines whether your neurons survive, branch, and build new connections. Here's what the peer-reviewed research actually shows about Lion's Mane.
Read Article
Mushroom powder and mushroom extract are not interchangeable. The difference between a dual-extracted fruiting body and a mycelium grain product is an order of magnitude in potency, and almost no brands will tell you why.
Read Article
At 4,300 metres on the Tibetan plateau, herders observed their yaks grazing on a strange parasitic fungus and becoming unusually powerful. Two thousand years later, Olympic coaches are running controlled trials.
Read Article
Reishi's most remarkable property isn't immune support: it's cortisol. Over 400 distinct triterpene compounds interact with the HPA axis in ways no other natural source can replicate. This is what 2,000 years of empirical use looks like under a microscope.
Read Article"I don't usually leave reviews. But after three months on the Melena de León, I had to. Sharper, calmer, more focused. Consistently."